Rochester NY
Lakeshore Records 370 Park Avenue, 14607 Pretty good store with a solid mix of new/used. Lots of CD's/DVD's as well.
Needle Drop Records (someone already mentioned this but it's worth including as well) 304 Gregory St, 14620 Great shop with much more new records. Great mix with a good deal of new/used 7" as well. My personal fav.
The Record Archive
33 1/2 Rockwood St, 14610
Some new, a whoooole lot of used. This place is really big with a good mix of cd's as well.